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Table 5 Antimycobacterial activities toward M. bovis BCG GL2 and cytotoxicity of extracts

From: Ethnobotanical survey and antimycobacterial activities of plants used against tuberculosis in Lubumbashi, DR Congo

Plant species

M. bovis BCG

SiHa

 

Microdilution

Agar proportion

Organ#

MIC50*

MIC99*

MIC50*

MIC99*

IC50*

SI

Methanolic extracts

 Acacia sieberiana DC. var. woodii

SB

 

208 ± 72

250

–

ND

ND

 Hexalobus monopetalus (A.Rich.) Engl.& Diels

LE

–

–

–

–

ND

ND

 Ochna afzelii R.Br. ex Oliv

LE

 

208 ± 72

–

–

ND

ND

 Parinari curatellifolia Planch.ex Benth

RO

 

62.5

 

125

20

0.16

 Phyllanthus muellerianus (Kuntze) Exell

RO

 

250

–

–

ND

ND

 Piliostigma thonningii (Schumach.) Milne-Redh

SB

–

–

–

–

ND

ND

 Rothmannia engleriana (K. Schum.) Keay

RO

250

–

–

–

ND

ND

 Securidaca longepedunculata Fresen

RO

–

–

–

–

ND

ND

 Strychnos spinosa Lam

SB

–

–

–

–

ND

ND

 Terminalia mollis M.A.Lawson

LE

–

–

–

–

ND

ND

 Zanthoxylum chalybeum Engl

RO

 

62.5

 

62.5

28

0.45

Aqueous extracts

 Parinari curatellifolia Planch.ex Benth

RO

 

–

250

ND

95

0.38

 Zanthoxylum chalybeum Engl

RO

 

–

 > 250

ND

34

ND

Controls

 Orlistat

     

133

 

 Rifampicine

 

ND

0.01

 

 < 0.06

  
  1. #SB: stem bark; RO: roots; LE: leaves
  2. *Concentration in μg/mL