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Table 3 Frequencies of SNPs and haplotypes in pfcrt and pfmdr1 P. falciparum samples

From: Mutational profile of pfdhfr, pfdhps, pfmdr1, pfcrt and pfk13 genes of P. falciparum associated with resistance to different antimalarial drugs in Osun state, southwestern Nigeria

 

Codon mutation

No. of isolates (n)

Frequency (%)

Genes

pfcrt (n = 297)

M74I

36

12.12

N75E

36

12.12

K76T

47

15.82

pfmdr1 (n = 262)

N86Y

7

2.67

E130K

0

0.00

Y184F

208

79.39

S1034C

0

0.00

N1042D

2

0.76

V1109I

0

0.00

D1246Y

3

1.15